“African trypanosomes: how they use quorum sensing and how it can be lost in the field”

Host: Prof Mike Ferguson

Venue: MSI, Small Lecture Theatre, SLS

Bio:

Keith Matthews undertook PhD research with Professor David Barry at the University of Glasgow focused on trypanosome metacyclic VSG regulation, graduating in 1990, and then was awarded a NATO postdoctoral fellowship to work on parasite RNA in the laboratory of Professor Elisabetta Ullu, at Yale University, USA. He returned to the UK in 1992 to the University of Manchester, working with Professor Keith Gull on trypanosome cell biology and differentiation. In 1996, he established his own laboratory at Manchester, before moving to the University of Edinburgh in 2004, being promoted to Professor of Parasite Biology in 2007. Subsequently he has acted as Director of the Centre for Immunity, Infection and Evolution and Head of Institute for Immunology and Infection Research, and directs the Wellcome PhD programme “Hosts, Pathogens and Global health”. He was elected Fellow of the Royal Society of Edinburgh (FRSE) in 2014, Fellow of the Academy of Medical Sciences (FMedSci) in 2018, and Fellow of the Royal Society (FRS) in 2020. He was awarded the 2008 BSP C. A. Wright medal, 2015 Sanofi-Pasteur mid-career award for contributions to Infectious disease research and the 2023 Alice and C. C. Wang award in molecular parasitology by the American Society for Biochemistry and Molecular Biology. Keith is currently a Wellcome Trust Investigator, leading a research programme focused on understanding environmental sensing and cell-cell communication in African trypanosomes.

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