Location
Tayside Centre for Genomic Analysis
The primary aim of the Centre is to provide genomic analysis services to the University of Dundee encompassing both academic and clinical research themes
School of Medicine
Mailbox 6, Level 6
University of Dundee
Ninewells Hospital
DD1 9SY
Accessibility
About
The primary aim of the Tayside Centre for Genomic Analysis is to provide a state-of-the-art next-generation sequencing (NGS), genotyping services and bioinformatics analysis to the University of Dundee encompassing both academic and clinical research themes. The service is also available to external research and clinical groups, capacity permitting. Funds accumulated through the successful operation of the service are used to support the continued development of the core service unit within the University of Dundee. The Centre endeavours to maintain an inexpensive service while providing state-of-the-art equipment to support the activities of its clients.
Services
The facility provides end-to-end service in all stages: from grant writing, experimental design to data analysis. We offer following standard and bespoke services including:
- Sample preparation (DNA/RNA extraction) from blood, FFPE, microbial samples, etc., using standard kits or using automated extraction instrument using KingFisher Flex.
- Quality Control using Agilent TapeStation 4200 and Qubit 3.0 Fluorometer.
- Next Generation Sequencing Library Preparation using Illumina kits, or any standard kits based on request.
- Our standard Next Generation sequencing services with pre-made libraries using both Illumina (MiSEQ) and Oxford Nanopore (MinION and GridION) are mRNA, total RNA, small RNA, whole genome, exome, targeted, amplicon (16S/18S/ITS) and metagenomics.
- Genotyping using Illumina (iScan)
- Standard quality control for both Illumina, and Oxford Nanopore sequencing data.
- Bioinformatics data analysis including genome-wide association analysis, genome assembly/alignment, RNA-sequencing, Exome sequencing, Metagenomics, Epigenomics and phenome-genome analysis, etc, using in-house scripts and/ existing or custom-made pipelines in Nextflow.
Equipment use
The TCGA also offers two Applied Biosystems Quantstudio 7 Flex real-time PCR instruments (96-well fast and 384-well blocks and an array card blocks (384-well TLDA) and GridION for use by users within or outside of the University of Dundee. Time on any of the above-mentioned instruments can be arranged using the Labshake, online lab management platform, (University of Dundee staff and students only) or by emailing us.
Find out more information about our services see TCGA website
Get a quote or discuss projects
If you have any queries or looking for quotes, please contact us by email: [email protected]. If you would like to discuss your project requirements, please contact Dr Gwen Kennedy ([email protected]) or Dr Abirami Veluchamy ([email protected]).