Advanced antibacterial surfaces for medical devices

Medical devices such as catheters, prosthetics, and orthopedic implants are frequently affected by bacterial biofilm formation, leading to persistent infections that are difficult to treat with conventional antibiotics. With antimicrobial resistance projected to claim 10 million lives annually by 2050, the development of alternative infection-prevention strategies is more urgent than ever.

This PhD project will explore an innovative hybrid approach to antibacterial surface engineering, combining ultrafast laser structuring with bioactive nanocomposite coatings. The integration of nature-inspired topographical surface modifications and advanced biopolymer coatings offers a highly promising route to antibiotic-free infection control.

You will work in state-of-the-art research laboratories with access to cutting-edge laser processing and biomaterials characterisation tools. You will be part of a thriving research community of scientists and PhD students at the University of Dundee. Through this project, you will develop expertise in laser processing, biomaterials, and microbiology, contributing to groundbreaking advancements in real-world applications in medical devices, implants, and infection prevention.

Key objectives and potential impact

• Laser-assisted surface structuring – Creating nano- and micro-scale textures inspired by natural antibacterial surfaces (e.g., cicada wings, sharkskin).

• Antibacterial coatings – Developing and optimising bioactive coatings.
• Hybrid surface engineering – Combining mechanical and chemical antibacterial mechanisms for enhanced biofilm resistance.

• Biomedical applications – Evaluating the performance of engineered surfaces against clinically relevant bacterial strains.

Any specific requirements for candidates

A minimum of a 1st BSc (or equivalent qualification level) in Mechanical or Biomedical Engineering, Physics, Chemistry, Materials Science, or another relevant degree with sufficient focus on one of these areas, e.g. Engineering or Natural Sciences.

Diversity statement

Our research community thrives on the diversity of students and staff which helps to make the University of Dundee a UK university of choice for postgraduate research. We welcome applications from all talented individuals and are committed to widening access to those who have the ability and potential to benefit from higher education.